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The impact of these channels on neuron firing rate in nigral dopamine neurons is such that administration of your KATP-channel antagonist glibenclamide in a 100 nM focus was in a position to increase neuron firing charge by 34% (Garcia de Arriba et al 1999; Avshalumov et al 2005). KATP-channel activity also seems to get increased by extracellular a

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